Hemophagocytic syndrome

Hemophagocytic lymphohistiocytosis (HLH), also known as hemophagocytic syndrome,^[1] is an uncommon hematologic disorder that, typically, clinically manifests as fever, hepatosplenomegaly, lymphadenopathy, jaundice and rash, with laboratory findings of histiocytosis,^[2] and the pathologic finding ofhemophagocytosis. Pancytopenia (anemia, neutropenia, and thrombocytopenia), markedly elevated serum ferritin levels, and abnormal liver enzymes are frequently present.